What cannot be cured must be endured.

When an unwelcome situation cannot be changed, a person has to find a way to live with it rather than continue looking for a remedy.

The proverb urges acceptance of an unavoidable difficulty. It does not suggest abandoning a problem while workable solutions remain.

Use it to acknowledge a difficulty that has no practical remedy, or to encourage patience with a constraint that must be lived with. Addressed to someone in distress, it may sound dismissive rather than comforting.